Which enzyme is responsible for converting Glucose 6-phosphate to Fructose 6-phosphate?

The enzyme that converts Glucose 6-phosphate to Fructose 6-phosphate is Phosphohexose isomerase. This enzyme facilitates an isomerization reaction, which means it rearranges the molecular structure of Glucose 6-phosphate to form Fructose 6-phosphate without adding or removing any atoms.

During this process, the carbonyl group of the aldehyde in Glucose 6-phosphate is converted into a ketone, resulting in Fructose 6-phosphate. This is a critical step in the glycolytic pathway, as it sets the stage for subsequent steps that ultimately lead to the production of energy in the form of ATP.

The other enzymes listed contribute to different reactions in metabolism. Hexokinase phosphorylates glucose to form Glucose 6-phosphate and does not play a role in converting Glucose 6-phosphate to Fructose 6-phosphate. Phosphofructokinase-1 is an important regulatory enzyme in glycolysis that converts Fructose 6-phosphate to Fructose 1,6-bisphosphate, and Aldolase catalyzes the cleavage of Fructose 1,6-bisphosphate into dihydro