Which conversion occurs during the bypass of step 3 in gluconeogenesis?

Study for the ACS Biochemistry Exam. Explore flashcards and multiple choice questions with hints and explanations. Prepare to excel in your exam!

During gluconeogenesis, the process involves bypassing steps of glycolysis that are energetically unfavorable and regulated. The conversion that occurs during the bypass of step 3 in gluconeogenesis involves the transformation of fructose 1,6-bisphosphate to fructose 6-phosphate.

This specific step is catalyzed by the enzyme fructose 1,6-bisphosphatase, which is crucial for gluconeogenesis because it helps to regulate the flow of metabolites and ensures that glucose is synthesized rather than broken down. This conversion is significant as it reverses one of the key regulatory steps in glycolysis, allowing for the synthesis of glucose from non-carbohydrate precursors.

In contrast, the other options do not correctly pertain to the bypass of step 3 in gluconeogenesis. For instance, the conversion of oxaloacetate to phosphoenolpyruvate occurs in an earlier step and is associated with the action of pyruvate carboxylase and phosphoenolpyruvate carboxykinase. Similarly, the conversions involving pyruvate to acetaldehyde and acetaldehyde to ethanol are part of alcoholic fermentation, not gluconeogenesis, and are unrelated to the metabolic pathway for

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