What is one of the functions of NADH in cellular metabolism?

Study for the ACS Biochemistry Exam. Explore flashcards and multiple choice questions with hints and explanations. Prepare to excel in your exam!

NADH plays a crucial role in cellular metabolism, particularly in the process of cellular respiration. Its primary function is to transport electrons to the electron transport chain, which is part of oxidative phosphorylation in the mitochondria. When NADH is generated during glycolysis, the citric acid cycle, and other metabolic pathways, it acts as a high-energy electron carrier.

In the electron transport chain, NADH donates electrons, which are then transported through a series of protein complexes. This electron transfer is vital for creating a proton gradient across the inner mitochondrial membrane, ultimately leading to the production of ATP through ATP synthase. Therefore, one of the central roles of NADH is indeed electron transport, making it indispensable for energy production in aerobic organisms.

The other functions listed, such as electrolyte balance, initiating glycolysis, and single-electron transfer, do not capture the primary and well-established role of NADH in cellular metabolism, which is centered around its involvement in electron transport and ATP generation.

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